Take this medication by mouth with a full glass of water. Follow the directions on the prescription label. If the medication upsets your stomach, take the medication with food or milk. Do not take more than you are told to take.
Talk to your care team about the use of this medication in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What Are Dosages of Butalbital/Acetaminophen/Caffeine?
Adult and pediatric dosage
Tablet
- butalbital/acetaminophen/caffeine
- 50mg/325mg/40mg (Fioricet, Esgic)
- 50mg/500mg/40mg (Espic-Plus)
- 50mg/750mg/40mg (Dolgic Plus)
Capsule
- butalbital/acetaminophen/caffeine
- 50mg/300mg/40mg (Orbivan)
- 50mg/325mg/40mg (Esgic, Margesic)
- 50mg/500mg/40mg (Esgic-Plus, Zebutal)
Liquid, oral
- butalbital/acetaminophen/caffeine
- (50mg/325mg/40mg)15mL (Alagesic LQ)
Tension Headache
Adult dosage
- 50mg/300-325mg/40mg: 2 tablets or capsules orally every 4 hours; not to exceed 6 tablets or capsules/day
- 50mg/500mg/40mg: 1 tablet/capsule orally every 4 hours; not to exceed 6 tablets or capsules/day
- 50mg/750mg/40mg: 1 tablet/capsule orally every 4 hours; not to exceed 5 tablets or capsules/day
- 15-30 mL solution orally every 4 hours; not to exceed 180 mL solution/day
- Not to exceed 4 g/day of acetaminophen for any dosage form or regimen
Pediatric dosage
- Children younger than 12 years of age: Safety and efficacy not established
- Children 12 years of age or older:
- 50mg/300-325mg/40mg: 2 tablets or capsules orally every 4 hours; not to exceed 6 tablets or capsules/day
- 50mg/500mg/40mg: 1 tablet/capsule orally every 4 hours; not to exceed 6 tablets or capsules/day
- 50mg/750mg/40mg: 1 tablet/capsule orally every 4 hours; not to exceed 5 tablets or capsules/day
- 15-30 mL solution orally every 4 hours; not to exceed 90 mL solution/day
- Not to exceed 4 g/day of acetaminophen for any dosage form or regimen
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.